Hybrid Capture 2 is as Effective as PCR Testing for High-risk Human Papillomavirus in Head and Neck Cancers
نویسندگان
چکیده
منابع مشابه
Clinical implications of human papillomavirus in head and neck cancers.
Human papillomavirus (HPV) is now recognized to play a role in the pathogenesis of a subset of head and neck squamous cell carcinomas (HNSCCs), particularly those that arise from the lingual and palatine tonsils within the oropharynx. High-risk HPV16 is identified in the overwhelming majority of HPV-positive tumors, which have molecular-genetic alterations indicative of viral oncogene function....
متن کاملSignificance of Human Papillomavirus in Head and Neck Cancers
© 2015 Harborside Press® Over 45,000 Americans are estimated to be newly diagnosed with cancer of the oral cavity and pharynx in 2015, and an estimated 8,650 will die of the disease (Siegel, Miller, & Jemal, 2015). It is well known that the combination of smoking and alcohol use increases the risk for developing head and neck squamous cell carcinoma (HNSCC). Head and neck squamous cell carcinom...
متن کاملHuman papillomavirus: a cause of some head and neck cancers?
Establishing a causal link between HPV and certain head and neck cancers would have implications for prognosis, prevention and therapy.
متن کاملHuman papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck.
BACKGROUND Oncogenic human papillomaviruses (HPVs), especially HPV type 16 (HPV-16), cause anogenital epithelial cancers and are suspected of causing epithelial cancers of the head and neck. METHODS To examine the relation between head and neck cancers and HPVs, we performed a nested case-control study within a joint Nordic cohort in which serum samples were collected from almost 900,000 subj...
متن کاملLow prevalence of high risk human papillomavirus in normal oral mucosa by hybrid capture 2
High risk human papillomavirus (HR-HPV) are recognized as a necessary factor to development cervical cancer. During the last decade many studies have found HR-HPV in oral squamous cell carcinoma (OSCC) and normal oral mucosa, however the association between HR-HPV and OSCC is still uncertain. The aim of the study was to determine DNA HR-HPV in normal oral cavity of healthy adults. A cross-secti...
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ژورنال
عنوان ژورنال: Applied Immunohistochemistry & Molecular Morphology
سال: 2015
ISSN: 1541-2016
DOI: 10.1097/pdm.0000000000000036